Job Information
J&J Family of Companies Senior Principal Scientist- iDerm, Translational Sciences, Immunology Translational Science & Medicine in Spring House, Pennsylvania
Senior Principal Scientist- iDerm, Translational Sciences, Immunology Translational Science & Medicine - 2406196731W
Description
Johnson and Johnson is currently seeking a Senior Principal Scientist, Translational Sciences (TS), Immunology Translational Sciences and Medicine (TSM) to be located in San Diego, CA or Spring House, PA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/ .
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong.
Translational Sciences and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end-to-end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies for these patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases.
TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision-making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. Expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development are highly desirable.
This position will reside within the ImmunoDermatology group in the Immunology Translational Sciences department and requires a highly motivated and skilled candidate to assist in the clinical progression of innovative therapies across diseases. The successful candidate will serve as a Translational Science Program Lead (TSPL) responsible for the development and implementation of translational strategy to support immunology portfolio assets. The successful candidate will be expected to lead a matrixed team with diverse expertise and will be responsible for the successful implement of high caliber translational biomarker packages. Further, the candidate will operate in a highly collaborative environment and deliver high quality to support key stakeholders such as the compound development teams, clinical trial teams, dermatology disease area stronghold and Translational Science and Medicine.The candidate will ensure delivery of completed data and analyses in support of key program milestones, drive technical excellence in translational science and biomarker research, contribute to the strategic direction of TS, and will take an active role in mentoring team members. Furthermore, the candidate will partner with cross-functional teams to engage in interactions with external experts and academic institutions to advance Immunology portfolio.
Responsibilities are as follows:
Develop and implement translational strategy to support compound development teams
Contribute to the strategies on molecular understanding of human diseases, patient stratification and novel biomarker-based endpoints in clinical trials
Manages external testing vendors and partners to ensure biomarker samples are tested and data is reported to meet development timelines and specifications
Communicate study results and provide guidance to stakeholders in applying those results for strategic decisions
Collaborate with bioinformaticians on data analysis plan from integrated multi-omic datasets
Take initiative to identify, pilot and validate emerging novel translational technologies to expand iDerm TS capabilities
Develop technical expertise and leadership potential of team members with particular focus on training the next wave of science leaders
Help build an extensive external network of leaders to enable strategic partnerships and awareness of advances in translational and biomarker research
Prepare and review of protocols, clinical study reports, IBs, INDs, abstracts, manuscripts, and technical reports
Qualifications
PhD or MD/PhD with at least 5 years or B.S. with at least 15 years of relevant experience is required, preferably in pharmaceutical or biotechnology sectors
Experienced in type 2 diseases (atopic dermatitis and asthma) and/or expertise in itch biology is strongly preferred
Experience in translational research, including biomarker analysis, patient stratification, and diagnostic approaches, in the industry setting is strongly preferred
Project leadership experienced in matrix environment is strongly preferred
Excellent communication skills
Dynamic entrepreneurial mindset
The anticipated base pay range for this position is $135,000 to $232,300.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
This position is eligible to participate in the Company’s long-term incentive program.
Employees are eligible for the following time off benefits:
Vacation – up to 120 hours per calendar year
Sick time - up to 40 hours per calendar year
Holiday pay, including Floating Holidays – up to 13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Additional information can be found through the link below. For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits
Primary Location NA-US-California-San Diego
Other Locations NA-US-Pennsylvania-Spring House
Organization Janssen Research & Development, LLC (6084)
Travel Yes, 10 % of the Time
Job Function Translational Discovery & Development Biomarkers
Req ID: 2406196731W