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J&J Family of Companies Associate Director, Gene Therapy Viral Technologies in Spring House, Pennsylvania

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for an Associate Director, Gene Therapy Viral Technologies, located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Associate Director Gene Therapy Viral Technologies position in Gene Therapy and Gene Delivery Platforms group of Janssen Therapeutics Discovery offers an exciting opportunity to help develop novel Gene Therapies for unmet medical needs. We are investigating the use of Adeno-Associated Virus (AAV) vectors to deliver therapeutic proteins to patients for disease prevention and treatment, especially for ophthalmological, neurological, and novel therapies for infectious disease.

We are seeking a highly motivated and independent researcher to lead the group that is actively testing and developing technologies to expand gene therapies to common diseases with millions of patients. The manufacturing challenge requires innovations in engineering viruses and the cell lines used to produce them. Increased virus potency and altered tropism will be necessary to develop effective treatments for some diseases. The successful candidate will play an important role in meeting these challenges and bringing innovative therapies to patients.

Primary Responsibilities

  • Lead a discovery research team developing innovative ways to produce viral vectors for Gene and Cell therapies at large scale through cellular- and virus-engineering, modulation of antiviral defenses, and inducible technologies.

  • Subject matter expert in AAV biology and viral manufacturing

  • Stay ahead of the AAV gene therapy field by identifying new technologies outside the company and collaborating to critically evaluate these technologies for potential in-licensing or acquisition

  • Closely mentor scientists to further develop talent within the group

  • Execute research timelines to meet program and corporate objectives

  • Foster a collaborative and creative culture of scientific discovery

Qualifications

Required:

  • Ph.D. in Virology, Biochemistry, Cell Biology, Molecular Biology, Biomedical Engineering, or related discipline with at least 10 years relevant post-graduate industry or academic experience.

  • Deep biological expertise in one or more eukaryotic viral vectors (including Adenovirus, AAV, Lentivirus, and Herpes Virus) and experience re-engineering viruses to change their potency, serotype, replicative properties, or packaging capacity.

  • Demonstrated leadership experience, including the ability to influence and collaborate with peers, to develop and mentor others, and to oversee and guide the work of colleagues to achieve meaningful outcomes and to create business impact.

  • Strong track record of scientific accomplishments directed towards discovery and development of therapeutic agents, including peer-reviewed first-author publications, patent applications, and/or presentations at major national meetings and participation in professional societies.

  • Must have excellent communication (both written and oral), time management, record keeping and data analysis and collaborative skills.

Preferred:

  • Experience engineering virus packaging cell lines or inducible virus-producer cell lines is highly valued.

  • Experience with AAV Gene Therapy vector construction and manufacturing.

At Johnson & Johnson, we’re on a mission to change the trajectory of health for humanity. That starts by creating the world’s healthiest workforce. Through cutting-edge programs and policies, we empower the physical, mental, emotional, and financial health of our employees and the ones they love. As such, candidates offered employment must show proof of COVID-19 vaccination or secure an approved accommodation prior to the commencement of employment to support the well-being of our employees, their families, and the communities in which we live and work.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location

United States-Pennsylvania-Spring House-Welsh & McKean Roads

Organization

Janssen Research & Development, LLC (6084)

Job Function

R&D

Requisition ID

2206078153W

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