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Position Description

The Miller and Singh Labs at Columbia University Mailman School of Public Health has opening for a Postdoctoral Research Scientist position with expertise in the field of exposomics, metabolomics, mass spectrometry, or cheminformatics. The Postdoctoral Research Scientist will work on an exciting funded project exploring the gene x environmental interactions and how they alter drug metabolism.

The Postdoctoral Research Scientist, under the supervision of the Principal Investigators in the Department of Environmental Health Sciences, will be responsible for studies utilizing high-resolution mass spectrometry. Duties assigned require an in-depth knowledge of small molecule analytical chemistry, high resolution mass spectrometry-based non-target analysis and data processing, drug and xenobiotic metabolism, and statistical analysis. General duties involve organizing and implementing complex research plans, developing high-throughput sample preparation, HRMS data collection and analysis, and writing reports containing descriptive, analytical, and evaluative content. All research activities will be conducted in accordance with the policies and standard practices of Columbia University.

Responsibilities include:

• Design, organize, and conduct highly specialized and advanced exposomic experiments (20%).
• Plan and conduct day-to-day experimental activities related to assigned research projects (15%).
• Conduct, collect, and analyze research data; create detailed documentation of experiments and research data (15%).
• Use graphics and statistical software to analyze and present data at conferences and for manuscript preparation (10%).
• Conduct scientific literature research to design new protocols and to prepare publications in scientific journals (10%).
• Assist in preparation of grant applications (10%).
• Design and implement research protocols; establish safety procedures; design new procedures, methods or instrumentation processes (5%).
• Prepare reagents and samples for experimental procedures, perform quality control and maintain equipment (5%)
• Provide supervision and guidance to staff, technicians, students, and researchers (5%)
• Performs all other duties as assigned (5%).

Minimum Qualifications:

• A doctoral degree in the appropriate field or the foreign equivalent is required.
• Thorough knowledge of the theories, techniques, and methods used in mass spectrometry and exposomics (sample prep and HRMS instrument handling and maintenance) and cheminformatic analyses.
• Knowledge and skill with computers and other statistical software as needed.
• Ability to communicate effectively both verbally and writing.
• Ability to maintain effective working relationships with supervisors, researchers, staff and other personnel. Excellent interpersonal and conflict resolution skills and work as team player.
• Ability to work collaboratively with other research institutions.
• Ability to complete all training and certification in compliance with the policies of the Columbia University and federal and state regulations.
• Prior experience with mass spectrometry, exposomics, and/or metabolomics.
• Prior experience studying environmental contributors to health.
• Ability to organize and prioritize within a changing environment. Demonstrate initiative and attention to detail.
• Excellent problem-solving skills and ability to troubleshoot protocols.
• Ability to work independently with minimal supervision.

Preferred Qualifications:

This successful applicant will be able to make substantial contributions to the fields of exposomics and metabolomics. It is expected that the applicant will have experience analyzing complex mass spectrometry data, it is possible that other cheminformatic skills could provide the necessary skillset.