Job Information
MCW: SARGEANT HEALTH CENTER Postdoctoral Fellow in MILWAUKEE, Wisconsin
JOB REQUIREMENTS: Position Description: We\'re looking for those individuals-the creative thinkers and innovation seekers-who are content with nothing short of changing the world. Discover the endless opportunities within the Medical College of Wisconsin (MCW) and be inspired by the work we can do together to improve health, and make a positive, daily impact in our communities. Position Summary Purpose: A Postdoctoral Fellow Position is immediately available in the laboratory of Dr. Anthony E. Zamora in the Division of Hematology and Oncology, Department of Medicine at the Medical College of Wisconsin. The Zamora lab\'s research focuses on identifying ways to modulate the immune system to more effectively target and eliminate cancerous cells. Along these lines, the lab utilizes cellular-based engineering approaches that aim to increase the specificity of immune cells for their targets and at the same time decrease the likelihood of off-target toxicities. Current research in the Zamora lab focuses on: (1) discovering tumor antigens that serve as immunogenic targets, (2) identifying the mechanisms involved in the immune system\'s ability to generate antitumor specificities, (3) characterizing the phenotypic, functional, and receptor repertoires of neoantigen-specific T cells, and (4) exploring ways to translate these findings to expand on the current therapeutic options used to treat cancer. A major area of focus for this postdoctoral position will be to work on preclinical and translational studies focused on assessing the efficacy of novel CAR T cell therapies. Work for this project will consist of determining whether non-viral genome targeting approaches utilizing endogenous gene expression pathways show improved persistence, functionality, and safety when compared to traditional non-targeted viral gene delivery systems. Experience with flow cytometry, PCR, RNA-seq, molecular cloning, cell culture, and other immunological techniques is required. Previous experience with sequencing, single-cell analysis, computational/bioinformatic analysis is highly desired. This position is NOT RESTRICTED to permanent U.S. residents or citizens. Characteristics of a postdoctoral appointment: It is expected that postdocs at MCW, with the assistance of their supervisor, will: Transition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his/her own choosing. Be supervised by at least one senior scholar who actively promotes the postdoc\'s professional development. Establish an individual development plan (IDP) that incorporates equally the... For full info follow application link. EEO/AA Minorities/Females/Vets/Disability The Medical College of Wisconsin is an affirmative action/equal opportunity employer and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, veteran status, disability or sexual orientation. ***** APPLICATION INSTRUCTIONS: Apply Online: ipc.us/t/B2F6ABE884A744BF Qualified females, minorities, and special disabled veterans and other veterans are encouraged to apply.