Job Information
AbbVie Senior Scientist I - In Vitro Pharmacology (Neurotoxin Discovery) in Irvine, California
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok (https://www.tiktok.com/@abbvie) .
Job Description
We are seeking a highly motivated Senior Scientist I who will lead efforts to design, execute, and communicate novel multi-disciplinary research in a highly collaborative neurotoxin discovery program. The Senior Scientist I will be an instrumental team member of the Toxins Innovation Group in Allergan Aesthetics, an AbbVie company, based in Irvine, CA.
The candidate will be responsible for planning, designing, implementing, and executing experiments to advance the development of new molecules. The candidate must have in-depth working knowledge of neuronal cell-based assays. He/She/They will be required to independently propose, design, and execute strategies while demonstrating exceptional troubleshooting skills. The candidate will independently organize, analyze and interpret results and make project recommendations. He/She/They will provide scientific leadership as a subject matter expert and provide feedback and guidance to a team of protein expression/purification, biophysical characterization, cell-based, and in vivo scientists. The candidate will also communicate and present his/her projects and results in team meetings and reports. He/She/They will collaborate extensively with other Research Scientists and Associates, while taking personal responsibility for the success of assigned tasks and projects.
The position requires the individual to work with and in areas requiring select agents and toxins access (i.e. Biosafety level 2 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, the candidate must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements. AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements, and objectives.
Key responsibilities:
In vitro characterization and MOA of new molecules.
Contribute to the development of cell-based models.
Generate detailed and accurate reports of study outcomes.
Actively participate on cross-functional teams and provide support to other groups and external departments. Openly share scientific expertise and collaboratively help the team to formulate rational solutions to problems.
Develop protocols, train staff, and maintain the laboratory consistent with departmental and company requirements.
Maintain a good and current knowledge of the scientific and technical literature pertinent to the project and necessary for development of state-of-the-art analytical methods, including the acquisition of necessary equipment.
Analyze and present results to multidisciplinary teams, prepare technical reports and contribute to driving strategy.
Qualifications
Minimum Qualifications:
Bachelor’s Degree + 10 years of experience OR Master’s Degree + 8 years of experience OR PhD and relevant research experience
Experience in performing mammalian cell culture and experimental protocols
Highly experienced with iPSC differentiation protocols to neurons
Experience with animal handling and post-mortem neuronal tissue harvest
Preferred Qualifications:
Experience with molecular biology (PCR, WB), immunological (ELISA) and histological (IHC, ICC, RNA scope) techniques, as well as microscopy techniques
Experience with electrophysiology and transcriptomic techniques.
Working experience with preclinical pain models in rodents
Experience in drug discovery
Other Required Skills:
- Demonstrated ability to work independently and in a highly collaborative team environment, multitask and ensure flexibility in a dynamic environment.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Salary: $91,500 - $173,500