Campus Pride Jobs

Job ID 12535 Location Case Main Campus Full/Part Time Full-Time Regular/Temporary Regular Strong Internal Identified A strong internal candidate has been identified. Job Description POSITION OBJECTIVE Working with a high degree of independence and under general direction from the principal investigator, the Research Assistant 4 will coordinate major experiments involving the study of retinal cholesterol homeostasis. This position will utilize a variety of experimental procedures ranging from routine procedures such as tissue collection, qRT-PCR, and histo/immunohistochemistry to highly complex procedures requiring high level of skills which include in-vivo ophthalmic characterizations by SD-OCT, different angiographies, fundus imaging, intraocular pressure measurements, various types of electroretinography, and visual acuity determination. Other highly complex procedures include establishing a corneal microbead mouse model, intravitreal injections, transmission electron microscopy, dissections of retina and optic nerve, and histological tracking of retinal lipoprotein by indocyanine green. The research assistant will also develop new methods of animal characterization per project needs. This position will work with animals. ESSENTIAL FUNCTIONS Coordinate major research activities in the laboratory under the two eye research project grants. This includes effort coordination of different lab members, ensuring compliance with animal protocol guidelines and requirements of the NIH, preparing Institutional Animal Care and Use Committee updates, and instrument repairs. Represent the lab in monthly departmental meetings, annual university Visual Sciences Research Center's symposium, and an annual major eye meeting. (12%) Provide input and recommendations to the principal investigator regarding research projects. Discuss with the principal investigator the overall project design, specific experiments, and data analysis plan with subsequent reports about the project progress and project future development. (10%) Perform the most complex quantitative analytical procedures. These include in vivo studies of mice and hamsters by: SD-OCT, different angiographies, fundus imaging, intraocular pressure and visual acuity measurements, and electroretinography. Utilize innovative research techniques requiring a high degree of skill and training such as microbead intravitreal injections to develop mouse model of glaucoma, tissue preparation for transmission electron microscopy, dissections of different parts of the eye and optic nerve. (40%) Assist in developing procedures, coordinate information with others as needed. Participate in development of procedures for lipoprotein particle isolation from the blood and retina and other methods that are required for research projects. Maintain and manage study protocols, description of research techniques and procedures. (6%) Teach or instruct others in research techniques. Train and supervise research assistant's 2 as well as students when they join the laboratory in histo/immunohistochemistry techniques, imaging, data analysis, and animal handling procedures in accordance with the institutional animal care and use committee procedure and guidelines. (6%) Co-author research projects. Participate in manuscript and grant writing, figure preparation, and all other activities that require a co-authorship on a manuscript and subsequent grant funding. (20%) May supervise research assistants and technicians. Provide detailed written instructions and tight supervision via daily meetings with a core manager to maintain all of the laboratory mouse strains. Supervise research assistants 2 and students (when joining the laboratory) in their daily activities. Assign daily tasks and manage daily progress daily. (6%) NONESSENTIAL FUNCTIONS Perform other duties as assigned. CONTACTS