Job Information
University of Michigan Research Lab Specialist Intermediate/ Research Lab Specialist Associate in Ann Arbor, Michigan
Research Lab Specialist Intermediate/ Research Lab Specialist Associate
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Summary
We are seeking a meticulous, well-organized, and team science-oriented researcher to join our Kidney Organoid Laboratory led by Dr. Jennifer Harder and expand our ability to model human kidney diseases. The Organoid Lab is one arm of the internationally recognized Michigan Kidney Translational Medicine Center, a highly collaborative multi-disciplinary 50+ member team with both wet and dry lab expertise led by Dr. Matthias Kretzler. Our shared mission is to identify molecular mechanisms of kidney disease to better inform diagnosis and treatment. For more information, see http://www.miktmc.org
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
Excellent medical, dental and vision coverage effective on your very first day
2:1 Match on retirement savings
Responsibilities*
Under the daily direction of our Research Lab Specialist Senior, you will help to do the following:
Generate, harvest and evaluate samples involving kidney organoid cultures and microphysiologic (microfluidics) systems for desired down-stream applications
Expand, passage, freeze/thaw and perform QC studies of stem cell and immortalized cell lines
Generate single cell suspensions of organoids for FACS and RNA sequencing
Facilitate Organoid Labs progress by working collaboratively with colleagues to generate, care for, harvest and share cell cultures and associated samples
Share responsibility for critical evening and weekend cell culture coverage needs with the organoid team
Perform molecular biology techniques involving RNA, DNA & protein isolation and quantification, EP-PCR, qRT-PCR, immunoblotting, ELISAs, cell fractionation, gel electrophoresis
Perform cryosectioning and immunohistochemistry/immunocytochemistry
Perform and analyze epifluorescence & confocal imaging of samples and perform data quantification
Design and iteratively optimize experiments with input & feedback from the organoid team
Investigate, develop, optimize, and integrate new reagents, techniques, assays and procedures in the laboratory as needed; prepare Standard Operating Procedures for associated protocols
Consistently maintain thorough inventory & data records shared by the organoid team
Share duties for meticulous organoid lab upkeep of tissue culture-related reagents, cell lines and plasticware inventory, lab equipment and general cell culture room maintenance which may involve planning/researching, cleaning, assembling, testing, calibrating or making minor repairs to equipment
Prepare, deliver and/or ship samples locally, nationally and internationally
Analyze data, generate images, and write methods for grants, presentations, progress reports and manuscript preparation under the direction of the Organoid Lab Director
Adhere to human subject research protections, regulatory oversight, and non-disclosure agreements
Work with the Organoid Lab & larger MiKTMC team to provide grant & funding deliverables on time
Attend weekly MiKTMC meeting, Office Hours with Organoid Lab Director, and Organoid Lab meeting
Required Qualifications*
Bachelor's degree in scientific field
Committment to generate high quality, reproducible data and to adhere to lab safety and regulatory requirements
High level of personal responsibility, meticulous attention to detail, great organization, communication and interpersonal skills, promptness and eagerness to be involved in a highly collaborative wet lab all a must
Ability to work indendently (after appropriate training period) as well as coopreatively
Flexiblity to cover shared responsibility for timed evening and weekend cell culture needs
Willingness to take direction from and be overseen by experienced colleagues & to share samples and data
Comfort with Excel, Word, Powerpoint applications as well as online resources for data analysis and presentation
Willing to make at least 3 year committment
Associate Requirements:
- Minimum 2 years of laboratory experience with (ideally advanced) techniques in cell culture & molecular biology
Intermediate Requirements:
- 4-5 years of laboratory experience with (ideally advanced) techniques in cell culture & molecular biology
Desired Qualifications*
Master's Degree or Doctoral Degree preferred.
Experience with stem cell cultures
Experience with cryosectioning, ICC/IHC and advanced microscopy
Experience with statistical analysis tools for biological data
Willingness to travel and present at conferences
Underfill Statement
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Application Deadline
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative action employer.
Job Detail
Job Opening ID
247653
Working Title
Research Lab Specialist Intermediate/ Research Lab Specialist Associate
Job Title
Research Lab Specialist Inter
Work Location
Ann Arbor Campus
Ann Arbor, MI
Full/Part Time
Full-Time
Regular/Temporary
Regular
FLSA Status
Exempt
Organizational Group
Medical School
Department
MM Int Med-Nephrology
Posting Begin/End Date
4/12/2024 - 5/10/2024
Career Interest
Research
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